Why reps in reserve wins
Sets taken close to failure, roughly 0 to 3 reps left, drive nearly all the growth of true failure with far less fatigue. That lets you keep quality across all your sets instead of gassing out on set one.
Stop most sets with 1 to 3 reps in reserve, and save true failure for the last set of isolation moves.
For most working sets, stop with 1 to 3 reps in reserve, meaning you could have done a couple more. Failure spikes fatigue and wrecks your next sets and next session without adding much growth. Reserve occasional failure for the final set of safe single joint moves like curls, leg extensions, and cable work, not heavy barbell squats, deadlifts, or bench.
Sets taken close to failure, roughly 0 to 3 reps left, drive nearly all the growth of true failure with far less fatigue. That lets you keep quality across all your sets instead of gassing out on set one.
Push to failure on isolation and machine work where a missed rep is safe, like leg extensions, lateral raises, and cable rows. Keep heavy compounds one to two reps shy so bar speed and form stay clean.
If your last two reps slow down noticeably and your form starts to break, you are near failure. Grinding reps where the bar barely moves means you went past the useful zone.
Stop most sets with 1 to 3 reps in reserve, and save true failure for the last set of isolation moves.