Volume is the driver, frequency is the tool
Total weekly hard sets matter most. Twice a week simply makes it easier to fit 10 to 20 quality sets in without any single session becoming a marathon of junk volume.
Yes, training each muscle about twice a week generally beats once for growth by spreading volume and refreshing the growth signal.
For most lifters, hitting a muscle twice a week edges out once a week at the same total volume, because you split the sets into two productive sessions instead of one huge fatiguing one. It also refreshes muscle protein synthesis roughly every 48 hours. What matters most is total weekly hard sets, around 10 to 20 per muscle, so use the frequency that lets you hit that with quality.
Total weekly hard sets matter most. Twice a week simply makes it easier to fit 10 to 20 quality sets in without any single session becoming a marathon of junk volume.
Splitting a muscle's work across two days means each set is done less fatigued, so you get more good reps and can push closer to failure with cleaner form.
If your split or schedule only allows once a week per muscle and you still get your volume in, you will still grow. Two times is a helpful default, not a strict rule.
Yes, training each muscle about twice a week generally beats once for growth by spreading volume and refreshing the growth signal.